Thrombocytopenia: When blood platelet counts are low which may cause serious bleeding even with minor scrapes, cuts, or bruises. High blood levels of calcium High levels of calcium in the blood called hypercalcemia can cause: Extreme thirst, leading to drinking a lot Urinating peeing a lot Dehydration Kidney problems and even kidney failure Severe constipation, Abdominal belly pain Loss of appetite Weakness Feeling drowsy Confusion If the level of calcium gets high enough, you can even slip into a coma.
Nervous system symptoms If myeloma weakens the bones in the spine, they can collapse and press on spinal nerves. This is called spinal cord compression and can cause Sudden severe back pain Numbness, most often in the legs Muscle weakness, most often in the legs. Nerve damage Sometimes, the abnormal proteins produced by myeloma cells are toxic to nerves. It can slow blood flow to the brain and cause: Confusion Dizziness Symptoms of a stroke, like weakness on one side of the body and slurred speech Patients with these symptoms should call their doctor.
This can lead to symptoms such as: Weakness Shortness of breath Itching Leg swelling. Infections Myeloma patients are much more likely to get infections. Signs and symptoms of light chain amyloidosis Patients with amyloidosis discussed in What Is Multiple Myeloma? They can also have other problems, such as: Heart problems : The heart may enlarge and become weaker.
In some people, the heart becomes so weak that fluid builds up in the lungs, making them feel short of breath. Fluid may also build up in the legs and feet edema. This is called congestive heart failure. This creates a space into which the bone cement is injected. The procedures are usually performed on an outpatient basis and can help improve mobility and quality of life.
For people for whom a kyphoplasty is not effective, our interventional radiology team is exploring whether it helps to insert a stabilizing rod through the skin for spine support.
This could avoid the need for surgery. Bone-Related Problems in Multiple Myeloma. Multiple Myeloma Symptoms. Multiple Myeloma Risk Factors. Multiple Myeloma Treatment. Other Plasma-Cell Diseases. Living Beyond Multiple Myeloma. Multiple Myeloma Clinical Trials. Multiple Myeloma Experts.
Slowing Bone Loss with Bisphosphonates Our doctors use a group of drugs called bisphosphonates to slow bone loss in people with myeloma. Shrinking Bone Tumors Bone damage can be treated using radiation therapy to the affected area. Spinal Problems Back pain is often the first symptom of multiple myeloma. You should notify your doctor immediately if you have these symptoms. Experts in Spine Stabilization Our doctors use a multidisciplinary approach to address damage to the vertebrae of the spine in people with multiple myeloma.
Minimally Invasive Spine Surgery Center. This content does not have an English version. This content does not have an Arabic version. Overview Multiple myeloma is a cancer that forms in a type of white blood cell called a plasma cell. Email address. First Name let us know your preferred name. Last Name. Thank you for subscribing Your in-depth coping with cancer guide will be in your inbox shortly. Sorry something went wrong with your subscription Please, try again in a couple of minutes Retry.
Request an Appointment at Mayo Clinic. Share on: Facebook Twitter. Show references Kaushansky K, et al. In: Williams Hematology. McGraw Hill; Accessed Sept. Ferri FF. Multiple myeloma. In: Ferri's Clinical Advisor Elsevier; Niederhuber JE, et al. Multiple myeloma and related disorders.
In: Abeloff's Clinical Oncology. National Comprehensive Cancer Network. Plasma cell neoplasms including multiple myeloma treatment PDQ — Patient version. National Cancer Institute. Distress management. Warner KJ. Allscripts EPSi.
0コメント